Across TCGA patient cohorts, ZSWIM9 mutation is significantly associated with the RNA expression of many other genes, with 605 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSWIM9-associated genes across cancer lineages are VN1R3, OR5T2, and RN7SKP25. Each is linked with ZSWIM9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSWIM9-to-partner and partner-to-ZSWIM9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM9→partner) and Y-score (partner→ZSWIM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	VN1R3 →	+0.042	+4.812	<.001	.006	3	1
CESC	OR5T2 →	+0.044	+6.164	<.001	<.001	3	1
CESC	RN7SKP25 →	+0.354	+4.364	<.001	.006	3	1
CESC	RN7SKP245 →	+0.129	+4.812	<.001	.006	3	1
CESC	RNU6-668P →	+0.610	+4.539	<.001	.008	3	1
CESC	CPLX3 →	+0.021	+5.342	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 605 associations by consensus.

Exploration

ZSWIM9 survival (RNA) · tumor vs normal (RNA) · all ZSWIM9 data types