Across TCGA patient cohorts, ZSWIM9 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSWIM9-associated genes across cancer lineages are eEF2, TIGAR, and 4E-BP1. Each is linked with ZSWIM9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSWIM9-to-partner and partner-to-ZSWIM9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM9→partner) and Y-score (partner→ZSWIM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.610	+3.169	.001	.020	3	1
UCEC	TIGAR →	+0.206	+3.196	.013	.010	3	1
UCEC	4E-BP1 →	+0.389	+3.029	.008	.018	3	1
UCEC	Cyclin-B1 →	+0.879	+3.169	.004	.020	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

ZSWIM9 survival (RNA) · tumor vs normal (RNA) · all ZSWIM9 data types