Across TCGA patient cohorts, ZSWIM8 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,167 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ZSWIM8-associated GO terms across cancer lineages are Protein-containing complex disassembly, Vacuole organization, and Positive regulation of autophagosome assembly. Each is linked with ZSWIM8 in more than 32 cancer types. Because this analysis shows association rather than direction, both ZSWIM8-to-partner and partner-to-ZSWIM8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM8→partner) and Y-score (partner→ZSWIM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Protein-containing complex disassembly →	+0.129	+1.140	<.001	<.001	3	33
SCLC	Vacuole organization →	+0.090	+0.925	<.001	<.001	3	33
SCLC	Positive regulation of autophagosome assembly →	+0.115	+0.674	<.001	<.001	2	33
THYM	Autophagosome organization →	+0.056	+1.008	<.001	<.001	3	32
SCLC	Positive regulation of autophagy →	+0.066	+0.808	<.001	<.001	3	32
SCLC	Regulation of macroautophagy →	+0.064	+0.787	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,167 associations by consensus.

Exploration

ZSWIM8 survival (RNA) · tumor vs normal (RNA) · all ZSWIM8 data types