Across TCGA patient cohorts, ZSWIM8 protein abundance is significantly associated with the RNA expression of many other genes, with 2,946 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZSWIM8-associated genes across cancer lineages are ACTR1A, MDM4P1, and ECD. Each is linked with ZSWIM8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZSWIM8-to-partner and partner-to-ZSWIM8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM8→partner) and Y-score (partner→ZSWIM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ACTR1A →	+0.572	+0.216	<.001	.002	3	4
UCEC	MDM4P1 →	-0.538	-0.158	.002	<.001	3	3
BRCA	ECD →	+0.432	+0.208	.001	<.001	3	3
LSCC	FAM149B1 →	+0.326	+0.132	<.001	.003	3	3
BRCA	MRPS16 →	+0.371	+0.158	.001	<.001	3	3
BRCA	AP3M1 →	+0.482	+0.163	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,946 associations by consensus.

Exploration

ZSWIM8 survival (RNA) · tumor vs normal (RNA) · all ZSWIM8 data types