ZSWIM8

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZSWIM8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,148 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSWIM8-associated GO terms across cancer lineages are Target-directed miRNA degradation, Cytosolic transport, and Macroautophagy. Each is linked with ZSWIM8 in more than 19 cancer types. Because this analysis shows association rather than direction, both ZSWIM8-to-partner and partner-to-ZSWIM8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM8→partner) and Y-score (partner→ZSWIM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaTarget-directed miRNA degradation →+0.170+1.839<.001<.001320
STOMACHCytosolic transport →+0.079+0.899.005.004319
STOMACHMacroautophagy →+0.071+0.824.001.002219
UPPER_AERODIGESTIVE_TRACTRetrograde transport, endosome to Golgi →+0.073+1.216<.001<.001317
LARGE_INTESTINEResponse to starvation →+0.053+0.938<.001<.001317
STOMACHProcess utilizing autophagic mechanism →+0.078+0.879.009.005317
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,148 associations by consensus.

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