Across TCGA pan-cancer cohorts, ZSWIM7 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ZSWIM7 data layer compared with 27 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZSWIM7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZSWIM7 expression acts as an unfavorable survival marker.

HNSC are the cancer types where ZSWIM7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.222	0.751	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: ZSWIM7 tumor-vs-normal RNA expression · all ZSWIM7 data types