Across TCGA patient cohorts, ZSWIM7 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSWIM7-associated genes across cancer lineages are MIR124-3, RNU6-1252P, and TSPY15P. Each is linked with ZSWIM7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSWIM7-to-partner and partner-to-ZSWIM7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM7→partner) and Y-score (partner→ZSWIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR124-3 →	+0.313	+7.640	<.001	.009	3	1
COAD	RNU6-1252P →	+0.526	+7.741	<.001	.009	3	1
COAD	TSPY15P →	+0.084	+7.741	<.001	.009	3	1
COAD	RNA5SP489 →	+0.518	+7.741	<.001	.009	3	1
COAD	OR5J7P →	+0.314	+7.741	<.001	.009	3	1
COAD	TEX101P1 →	+0.186	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

ZSWIM7 survival (RNA) · tumor vs normal (RNA) · all ZSWIM7 data types