ZSWIM7

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZSWIM7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,130 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZSWIM7-associated GO terms across cancer lineages are L-serine metabolic process, L-serine catabolic process, and Establishment of skin barrier. Each is linked with ZSWIM7 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZSWIM7-to-partner and partner-to-ZSWIM7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM7→partner) and Y-score (partner→ZSWIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCL-serine metabolic process →+0.178+0.876<.001.001310
LUNG_SCLCL-serine catabolic process →+0.259+0.975<.001<.00139
BLOOD_LeukemiaEstablishment of skin barrier →-0.106-1.042<.001<.00139
URINARY_TRACTD-amino acid metabolic process →+1.146+1.074<.001.00139
LARGE_INTESTINEPositive regulation of transcription initiation by RNA polymerase II →+0.049+0.811.001<.00139
LUNG_SCLCRegulation of establishment of protein localization to chromosome →+0.129+0.987<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,130 associations by consensus.

Exploration