ZSWIM6

Across TCGA patient cohorts, ZSWIM6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,994 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZSWIM6-associated genes across cancer lineages are RNU4-16P, RN7SL325P, and FDPSP5. Each is linked with ZSWIM6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSWIM6-to-partner and partner-to-ZSWIM6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZSWIM6 versus RNU4-16P in LSCC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM6→partner) and Y-score (partner→ZSWIM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNU4-16P →	+1.260	+1.119	<.001	.008	3	1
LSCC	RN7SL325P →	+0.276	+1.097	<.001	.004	3	1
LSCC	FDPSP5 →	+0.130	+1.097	.004	.004	2	1
LSCC	RPSAP71 →	+0.760	+1.133	<.001	.007	2	1
LSCC	SI →	+0.016	+1.097	.007	.004	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 2,994 associations by consensus.

ZSWIM6 vs RNU4-16P — LSCC

Explore this scatter interactively →