ZSWIM5P1

Across TCGA pan-cancer cohorts, ZSWIM5P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ZSWIM5P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ZSWIM5P1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZSWIM5P1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

KIRP and THCA are the cancer types where ZSWIM5P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZSWIM5P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	−0.016	.046	2	view →
THCA	All	II,III,IV	+0.007	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

ZSWIM5P1–KIRP

Open the KIRP breakdown →