ZSWIM5

Across TCGA patient cohorts, ZSWIM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,011 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZSWIM5-associated proteins across cancer lineages are GPX8, ACTR2, and ACTR3. Each is linked with ZSWIM5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZSWIM5-to-partner and partner-to-ZSWIM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZSWIM5 versus GPX8 in GBM, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM5→partner) and Y-score (partner→ZSWIM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GPX8 →	-0.721	-0.583	<.001	<.001	3	6
CCRCC	ACTR2 →	-0.194	-0.873	<.001	<.001	3	5
CCRCC	ACTR3 →	-0.216	-0.748	<.001	.002	3	5
GBM	FNDC3B →	-0.501	-0.695	<.001	<.001	3	5
LSCC	FNDC3B_S208 →	-0.489	-0.703	.001	<.001	3	5
GBM	GFPT2 →	-0.740	-0.576	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,011 associations by consensus.

ZSWIM5 vs GPX8 — GBM

Explore this scatter interactively →