ZSWIM5

Across TCGA cell cohorts, ZSWIM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,259 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZSWIM5-associated GO terms across cancer lineages are Copper ion export, Blood coagulation, intrinsic pathway, and Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure. Each is linked with ZSWIM5 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZSWIM5-to-partner and partner-to-ZSWIM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by ZSWIM5-low versus ZSWIM5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM5→partner) and Y-score (partner→ZSWIM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Copper ion export →	-0.173	-0.857	.001	<.001	3	12
BREAST	Blood coagulation, intrinsic pathway →	-0.346	-1.120	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure →	-1.391	-1.392	.003	.008	3	11
BREAST	Extracellular structure organization →	-0.112	-1.027	<.001	<.001	2	12
BREAST	Extracellular matrix organization →	-0.112	-1.077	<.001	<.001	2	12
LARGE_INTESTINE	Dentinogenesis →	-1.230	-1.195	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,259 associations by consensus.

Copper ion export by ZSWIM5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →