ZSWIM3

Across TCGA patient cohorts, ZSWIM3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,530 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZSWIM3-associated genes across cancer lineages are PFN3, OR6Y1, and RN7SKP95. Each is linked with ZSWIM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSWIM3-to-partner and partner-to-ZSWIM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZSWIM3 versus PFN3 in HNSC, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM3→partner) and Y-score (partner→ZSWIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PFN3 →	+0.202	+2.369	<.001	.003	3	1
HNSC	OR6Y1 →	+0.023	+2.707	.002	.001	3	1
LSCC	RN7SKP95 →	+0.988	+0.813	<.001	.007	3	1
LSCC	RNU6-251P →	+0.931	+0.813	.004	.007	3	1
LSCC	RNVU1-33 →	+0.701	+0.813	.002	.007	3	1
LSCC	GAPDHP28 →	+0.092	+1.043	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,530 associations by consensus.

ZSWIM3 vs PFN3 — HNSC

Explore this scatter interactively →