ZSWIM3

Across TCGA patient cohorts, ZSWIM3 protein abundance is significantly associated with the protein abundance of many other proteins, with 4,971 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZSWIM3-associated proteins across cancer lineages are NF1, ARHGAP9, and PPP1R18_S195. Each is linked with ZSWIM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSWIM3-to-partner and partner-to-ZSWIM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZSWIM3 versus NF1 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM3→partner) and Y-score (partner→ZSWIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NF1 →	+0.496	+1.652	<.001	<.001	3	1
BRCA	ARHGAP9 →	-0.499	-1.450	.001	.001	3	1
LUAD	PPP1R18_S195 →	+0.552	+0.525	.001	.002	3	1
BRCA	SCAF1_T976 →	-1.489	-2.205	<.001	.007	3	1
BRCA	USP9X_S2443 →	-0.467	-1.591	<.001	.002	3	1
BRCA	CHGB_Y341 →	+3.412	+1.763	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,971 associations by consensus.

ZSWIM3 vs NF1 — BRCA

Explore this scatter interactively →