ZSCAN9

Across TCGA patient cohorts, ZSCAN9 mutation is significantly associated with the RNA expression of many other genes, with 814 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN9-associated genes across cancer lineages are RNU6-933P, TRAJ11, and RN7SL332P. Each is linked with ZSCAN9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN9-to-partner and partner-to-ZSCAN9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-933P grouped by ZSCAN9-low versus ZSCAN9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN9→partner) and Y-score (partner→ZSCAN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-933P →	+0.449	+2.699	<.001	<.001	3	2
COAD	TRAJ11 →	+1.559	+4.958	<.001	<.001	3	2
UCEC	RN7SL332P →	+0.106	+3.231	<.001	.004	3	2
UCEC	RNA5SP415 →	+0.570	+2.225	<.001	.008	3	2
BLCA	RNU2-15P →	+0.202	+7.640	<.001	.009	3	2
SKCM	RNU4-45P →	+0.231	+6.810	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 814 associations by consensus.

RNU6-933P by ZSCAN9 expression — UCEC

Explore this box plot interactively →