ZSCAN9

Across TCGA cell cohorts, ZSCAN9 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZSCAN9-associated genes across cancer lineages are TAS2R7, KRTAP1-1, and ARMS2. Each is linked with ZSCAN9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN9-to-partner and partner-to-ZSCAN9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R7 grouped by ZSCAN9-low versus ZSCAN9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN9→partner) and Y-score (partner→ZSCAN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TAS2R7 →	+0.028	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP1-1 →	+0.136	+5.969	<.001	.001	3	1
BLOOD_Leukemia	ARMS2 →	+0.024	+4.922	<.001	.009	3	1
LARGE_INTESTINE	RASGEF1C →	+0.227	+3.404	.004	.006	3	1
LARGE_INTESTINE	CCDC195 →	+0.045	+3.297	<.001	.002	3	1
SKIN	GML →	+0.034	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

TAS2R7 by ZSCAN9 expression — BLOOD_Leukemia

Explore this box plot interactively →