ZSCAN5DP

Across TCGA pan-cancer cohorts, ZSCAN5DP RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ZSCAN5DP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZSCAN5DP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZSCAN5DP expression acts as an unfavorable survival marker, although some lineages such as BLCA and CESC show a favorable association.

KIRC, BLCA, and MESO are the cancer types where ZSCAN5DP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.449	0.713	<.001	74	view →
BLCA	OS	Quartile	All	0.788	0.615	.001	67	view →
MESO	DFS	Median	All	0.263	0.452	<.001	62	view →
LGG	DFS	Tertile	All	0.644	0.818	<.001	32	view →
CESC	OS	Quartile	All	0.883	0.714	.006	28	view →
CHOL	DFS	Quartile	All	0.151	0.570	.001	25	view →
LUSC	OS	Median	All	0.724	0.591	.002	17	view →
HNSC	OS	Tertile	All	0.838	0.702	.004	17	view →
UCS	DFS	Tertile	IV	0.956	0.312	.024	12	view →
THCA	DFS	Tertile	All	0.917	0.762	.008	11	view →
PAAD	OS	Median	II,III,IV	0.596	0.325	.014	9	view →
LIHC	OS	Median	All	0.464	0.688	.015	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ZSCAN5DP–KIRC (DFS)

Open the KIRC breakdown →