ZSCAN4

Across TCGA patient cohorts, ZSCAN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,292 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ZSCAN4-associated proteins across cancer lineages are MAMDC2, DDX21, and CHAF1A. Each is linked with ZSCAN4 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZSCAN4-to-partner and partner-to-ZSCAN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZSCAN4 versus MAMDC2 in HNSC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN4→partner) and Y-score (partner→ZSCAN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MAMDC2 →	+0.602	+0.522	<.001	.002	3	4
LUAD	DDX21 →	-0.526	-0.631	<.001	<.001	3	4
UCEC	CHAF1A →	-0.479	-0.194	.002	.001	3	4
HNSC	DNAJC7 →	-0.251	-0.357	<.001	<.001	3	4
UCEC	EZH2 →	-0.394	-0.445	.004	.004	3	4
UCEC	CENPF_S3079 →	-0.808	-0.210	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,292 associations by consensus.

ZSCAN4 vs MAMDC2 — HNSC

Explore this scatter interactively →