ZSCAN4

Across TCGA cell cohorts, ZSCAN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,298 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ZSCAN4-associated GO terms across cancer lineages are Cellular response to starvation, Cellular response to nutrient levels, and Tissue regeneration. Each is linked with ZSCAN4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZSCAN4-to-partner and partner-to-ZSCAN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to starvation grouped by ZSCAN4-low versus ZSCAN4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN4→partner) and Y-score (partner→ZSCAN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cellular response to starvation →	+0.059	+0.294	.001	.007	3	8
UPPER_AERODIGESTIVE_TRACT	Cellular response to nutrient levels →	+0.038	+0.348	.002	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Tissue regeneration →	+0.106	+0.554	<.001	<.001	3	8
STOMACH	Cellular response to amino acid starvation →	+0.066	+0.295	.002	.009	3	6
LUNG_SCLC	COPII vesicle coating →	+0.074	+0.114	.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell adhesion →	+0.080	+0.429	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,298 associations by consensus.

Cellular response to starvation by ZSCAN4 expression — STOMACH

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