ZSCAN32

Across TCGA pan-cancer cohorts, ZSCAN32 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZSCAN32 data layer compared with 25 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZSCAN32 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZSCAN32 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD, UCEC, and CHOL are the cancer types where ZSCAN32 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.302	0.700	.025	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
SKCM	DFS	Median	All	1.000	0.614	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZSCAN32–LUAD (OS)

Open the LUAD breakdown →