ZSCAN31

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZSCAN31 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZSCAN31 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZSCAN31 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZSCAN31 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC and LUAD are the cancer types where ZSCAN31 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSQuartileAll0.9540.724.0226view →
LUADDFSTertileAll0.7830.978.0024view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZSCAN31–UCEC (DFS)

Kaplan–Meier survival curve for ZSCAN31 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration