ZSCAN31

Across TCGA pan-cancer cohorts, ZSCAN31 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ZSCAN31’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ZSCAN31 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ZSCAN31 is over-expressed in tumor, although a few such as LSCC and PDAC show the opposite, repressed pattern.

LUAD, LSCC, and PDAC are the cancer types where ZSCAN31 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZSCAN31 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	+0.416	<.001	6	view →
LSCC	Male	All	−0.261	<.001	3	view →
PDAC	All	All	−0.573	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ZSCAN31–LUAD

Open the LUAD breakdown →