Across TCGA pan-cancer cohorts, ZSCAN30 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZSCAN30 data layer compared with 23 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZSCAN30 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ZSCAN30 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, GBM, and PRAD are the cancer types where ZSCAN30 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.941	0.300	.004	26	view →
GBM	OS	Median	All	0.024	0.416	<.001	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: ZSCAN30 tumor-vs-normal RNA expression · all ZSCAN30 data types