ZSCAN30

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZSCAN30 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZSCAN30 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZSCAN30 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ZSCAN30 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC and GBM are the cancer types where ZSCAN30 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianAll1.0000.802.0372view →
GBMOSMedianAll0.4990.240.0332view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration