Across TCGA cell cohorts, ZSCAN30 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSCAN30-associated genes across cancer lineages are KRTAP5-6, ECE2, and OR1C1. Each is linked with ZSCAN30 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN30-to-partner and partner-to-ZSCAN30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN30→partner) and Y-score (partner→ZSCAN30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KRTAP5-6 →	+0.312	+4.874	<.001	.002	3	1
LARGE_INTESTINE	ECE2 →	+0.353	+4.054	<.001	.004	3	1
LARGE_INTESTINE	OR1C1 →	+0.076	+3.684	<.001	.006	3	1
LARGE_INTESTINE	DCANP1 →	+0.014	+4.347	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

ZSCAN30 survival (RNA) · tumor vs normal (RNA) · all ZSCAN30 data types