ZSCAN25

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZSCAN25 mutation is significantly associated with the RNA expression of many other genes, with 3,691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN25-associated genes across cancer lineages are RNU6-14P, RNA5SP412, and RNU4-90P. Each is linked with ZSCAN25 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN25-to-partner and partner-to-ZSCAN25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN25→partner) and Y-score (partner→ZSCAN25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU6-14P →+0.498+5.669<.001.00332
UCECRNA5SP412 →+0.429+1.719.001.00632
BLCARNU4-90P →+0.243+4.588<.001.00832
BLCARNU6-1318P →+0.309+4.588<.001.00832
SKCMALDOA →+0.594+3.240.007.00932
UCECCCDC3 →-0.684-2.523.005<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

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