Across TCGA patient cohorts, ZSCAN25 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN25-associated genes across cancer lineages are TFRC, Di-Ras3, and eIF4E. Each is linked with ZSCAN25 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN25-to-partner and partner-to-ZSCAN25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN25→partner) and Y-score (partner→ZSCAN25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.458	+1.847	.018	.008	3	2
UCEC	Di-Ras3 →	-0.139	-3.446	.010	.005	3	2
UCEC	eIF4E →	+0.180	+3.183	.020	.009	3	1
UCEC	eIF4G →	+0.262	+2.459	.021	.019	3	1
UCEC	A-Raf_pS299 →	-0.093	-2.115	.034	.017	3	1
UCEC	Gab2 →	+0.278	+1.502	.034	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

ZSCAN25 survival (RNA) · tumor vs normal (RNA) · all ZSCAN25 data types