Across TCGA cell cohorts, ZSCAN25 mutation is significantly associated with the drug of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZSCAN25-associated genes across cancer lineages are FGFR_0939, AZD5991, and LY2109761. Each is linked with ZSCAN25 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN25-to-partner and partner-to-ZSCAN25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN25→partner) and Y-score (partner→ZSCAN25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FGFR_0939 →	+0.298	+2.999	.024	.028	3	1
BLOOD_Leukemia	AZD5991 →	-1.082	-2.952	.005	.026	3	1
BLOOD_Leukemia	LY2109761 →	-0.247	-3.000	.036	.028	3	1
BLOOD_Leukemia	Ara-G →	+0.762	+3.038	.004	.013	3	1
BLOOD_Leukemia	PD0325901 →	-0.882	-2.893	.018	.030	1	2
BLOOD_Leukemia	SCH772984 →	-0.616	-2.964	.023	.029	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ZSCAN25 survival (RNA) · tumor vs normal (RNA) · all ZSCAN25 data types