Across TCGA patient cohorts, ZSCAN23 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN23-associated genes across cancer lineages are Shc_pY317, Caspase-7-cleavedD198, and 4E-BP1. Each is linked with ZSCAN23 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN23-to-partner and partner-to-ZSCAN23 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN23→partner) and Y-score (partner→ZSCAN23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.198	-2.459	.003	.019	3	2
UCEC	Caspase-7-cleavedD198 →	+0.795	+3.341	.002	.005	3	2
UCEC	4E-BP1 →	+0.318	+3.029	.009	.018	3	2
UCEC	JNK2 →	+0.186	+2.000	.038	.032	2	2
UCEC	MEK1 →	+0.332	+3.321	.044	.010	3	1
UCEC	Rab25 →	-0.373	-3.169	.012	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ZSCAN23 survival (RNA) · tumor vs normal (RNA) · all ZSCAN23 data types