ZSCAN22

Across TCGA cell cohorts, ZSCAN22 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZSCAN22-associated genes across cancer lineages are MAGEB18 and TEX48. Each is linked with ZSCAN22 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN22-to-partner and partner-to-ZSCAN22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB18 grouped by ZSCAN22-low versus ZSCAN22-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN22→partner) and Y-score (partner→ZSCAN22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MAGEB18 →	+0.132	+4.152	<.001	.009	3	1
BLOOD_Leukemia	TEX48 →	+0.047	+5.060	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MAGEB18 by ZSCAN22 expression — BLOOD_Leukemia

Explore this box plot interactively →