Across TCGA patient cohorts, ZSCAN16 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN16-associated genes across cancer lineages are RNA5-8SP7, TRDJ2, and TRDJ3. Each is linked with ZSCAN16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN16-to-partner and partner-to-ZSCAN16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN16→partner) and Y-score (partner→ZSCAN16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5-8SP7 →	+0.452	+4.132	<.001	.009	3	2
COAD	TRDJ2 →	+1.198	+4.384	<.001	.006	3	1
COAD	TRDJ3 →	+1.256	+4.951	<.001	.002	3	1
UCEC	KIR3DL1 →	+0.309	+3.495	.001	.008	3	1
BRCA	RNU6-562P →	+0.266	+4.540	.001	.009	3	1
BRCA	RNA5SP463 →	+0.503	+4.513	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

ZSCAN16 survival (RNA) · tumor vs normal (RNA) · all ZSCAN16 data types