Across TCGA pan-cancer cohorts, ZSCAN12P1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ZSCAN12P1 data layer.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ZSCAN12P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZSCAN12P1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UVM show a favorable association.
KIRP, KIRC, and LUSC are the cancer types where ZSCAN12P1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.