ZSCAN12

Across TCGA cell cohorts, ZSCAN12 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZSCAN12-associated genes across cancer lineages are KRTAP19-3, PTH, and TEX26. Each is linked with ZSCAN12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN12-to-partner and partner-to-ZSCAN12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-3 grouped by ZSCAN12-low versus ZSCAN12-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN12→partner) and Y-score (partner→ZSCAN12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRTAP19-3 →	+0.132	+5.228	<.001	.005	3	2
LUNG_NSCLC_LUAD	PTH →	+0.045	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	TEX26 →	+0.025	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR56A5 →	+0.052	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.049	+5.228	<.001	.005	3	1
LARGE_INTESTINE	TAFA1 →	+0.402	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

KRTAP19-3 by ZSCAN12 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →