ZSCAN1

Across TCGA cell cohorts, ZSCAN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,203 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZSCAN1-associated GO terms across cancer lineages are Regulation of monoatomic cation transmembrane transport, Regulation of monoatomic ion transmembrane transport, and Negative regulation of transcription by RNA polymerase I. Each is linked with ZSCAN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZSCAN1-to-partner and partner-to-ZSCAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of monoatomic cation transmembrane transport grouped by ZSCAN1-low versus ZSCAN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN1→partner) and Y-score (partner→ZSCAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of monoatomic cation transmembrane transport →	-0.097	-1.284	<.001	<.001	3	7
BONE	Regulation of monoatomic ion transmembrane transport →	-0.095	-1.400	<.001	<.001	3	6
OVARY	Negative regulation of transcription by RNA polymerase I →	+0.075	+0.561	.009	.007	3	5
BONE	Regulation of homotypic cell-cell adhesion →	-0.096	-1.634	<.001	<.001	3	5
BONE	Positive regulation of monoatomic ion transport →	-0.102	-1.068	<.001	<.001	3	5
CNS	Keratinocyte proliferation →	-0.557	-0.345	.006	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,203 associations by consensus.

Regulation of monoatomic cation transmembrane transport by ZSCAN1 expression — BONE

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