ZSCAN1

Across TCGA cell cohorts, ZSCAN1 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ZSCAN1-associated genes across cancer lineages are OR52B2, CT45A10, and CT45A2. Each is linked with ZSCAN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN1-to-partner and partner-to-ZSCAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52B2 grouped by ZSCAN1-low versus ZSCAN1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN1→partner) and Y-score (partner→ZSCAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR52B2 →	+0.024	+4.981	.004	.008	3	2
LUNG_NSCLC_LUAD	CT45A10 →	+2.376	+3.367	<.001	.008	3	2
LUNG_NSCLC_LUAD	CT45A2 →	+0.827	+2.980	.008	.007	3	2
SKIN	HTR3D →	+0.010	+4.022	<.001	.006	3	2
LUNG_NSCLC_LUAD	MT1HL1 →	+0.074	+3.944	<.001	.006	3	1
LUNG_NSCLC_LUAD	CT45A3 →	+1.750	+3.343	.009	.008	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

OR52B2 by ZSCAN1 expression — CNS

Explore this box plot interactively →