ZRSR2

Across TCGA patient cohorts, ZRSR2 mutation is significantly associated with the RNA expression of many other genes, with 1,878 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZRSR2-associated genes across cancer lineages are CDY8P, RNU5E-8P, and RNU6-554P. Each is linked with ZRSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZRSR2-to-partner and partner-to-ZRSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDY8P grouped by ZRSR2-low versus ZRSR2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRSR2→partner) and Y-score (partner→ZRSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDY8P →	+0.054	+7.930	<.001	.008	3	2
COAD	RNU5E-8P →	+0.435	+5.142	<.001	.002	3	1
COAD	RNU6-554P →	+0.857	+3.730	<.001	.006	3	1
COAD	LINC01795 →	+0.098	+4.283	.005	.001	3	1
COAD	UBDP1 →	+0.090	+4.917	.001	.003	3	1
COAD	RN7SL83P →	+0.366	+4.392	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,878 associations by consensus.

CDY8P by ZRSR2 expression — LUAD

Explore this box plot interactively →