ZRSR2

Across TCGA patient cohorts, ZRSR2 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZRSR2-associated genes across cancer lineages are eEF2, eIF4E, and A-Raf_pS299. Each is linked with ZRSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZRSR2-to-partner and partner-to-ZRSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ZRSR2-low versus ZRSR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRSR2→partner) and Y-score (partner→ZRSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.334	+3.321	.023	.009	3	1
UCEC	eIF4E →	+0.245	+3.472	.004	.002	3	1
UCEC	A-Raf_pS299 →	-0.105	-2.321	.032	.034	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.447	+2.321	.033	.006	3	1
UCEC	MEK1 →	+0.490	+3.584	.001	.002	3	1
UCEC	p27_pT198 →	+0.088	+2.321	.046	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

eEF2 by ZRSR2 expression — UCEC

Explore this box plot interactively →