ZRANB3

Across TCGA cell cohorts, ZRANB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,623 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZRANB3-associated GO terms across cancer lineages are Negative regulation of DNA repair, DNA replication initiation, and Double-strand break repair. Each is linked with ZRANB3 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZRANB3-to-partner and partner-to-ZRANB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA repair grouped by ZRANB3-low versus ZRANB3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRANB3→partner) and Y-score (partner→ZRANB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of DNA repair →	+0.092	+0.633	<.001	<.001	3	15
BONE	DNA replication initiation →	+0.185	+0.566	<.001	<.001	3	15
BONE	Double-strand break repair →	+0.072	+0.460	.004	.005	3	15
UPPER_AERODIGESTIVE_TRACT	Somatic cell DNA recombination →	+0.096	+1.056	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Somatic diversification of immune receptors via germline recombination within a single locus →	+0.096	+1.056	<.001	<.001	3	15
BONE	Regulation of cell cycle G2/M phase transition →	+0.073	+0.531	.003	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,623 associations by consensus.

Negative regulation of DNA repair by ZRANB3 expression — BONE

Explore this box plot interactively →