ZRANB3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZRANB3 mutation is significantly associated with the RNA expression of many other genes, with 233 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZRANB3-associated genes across cancer lineages are ZNF804B, TPPP, and CELA1. Each is linked with ZRANB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZRANB3-to-partner and partner-to-ZRANB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF804B grouped by ZRANB3-low versus ZRANB3-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRANB3→partner) and Y-score (partner→ZRANB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHZNF804B →+0.012+4.285<.001.00732
LARGE_INTESTINETPPP →+0.935+3.502.001.00132
OESOPHAGUSCELA1 →+0.088+3.432<.001.00131
OESOPHAGUSGIP →+0.228+3.115<.001.00531
BREASTACTL9 →+0.010+4.781<.001.00331
BLOOD_LeukemiaCABP5 →+0.028+3.705.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 233 associations by consensus.

ZNF804B by ZRANB3 expression — STOMACH

Box plot of ZNF804B in ZRANB3-low vs ZRANB3-high samples in STOMACH.

Explore this box plot interactively →

Exploration