ZRANB2

Across TCGA cell cohorts, ZRANB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,670 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZRANB2-associated GO terms across cancer lineages are Regulation of telomere maintenance, Centriole replication, and Microtubule polymerization. Each is linked with ZRANB2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZRANB2-to-partner and partner-to-ZRANB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by ZRANB2-low versus ZRANB2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRANB2→partner) and Y-score (partner→ZRANB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.078	+1.346	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Centriole replication →	+0.107	+1.329	.001	<.001	3	16
LARGE_INTESTINE	Microtubule polymerization →	+0.141	+1.038	<.001	<.001	3	15
STOMACH	Protein modification by small protein removal →	+0.052	+0.614	.005	.005	3	15
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.092	+1.209	<.001	<.001	3	15
URINARY_TRACT	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.099	+0.841	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,670 associations by consensus.

Regulation of telomere maintenance by ZRANB2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →