ZRANB2-AS1

Across TCGA pan-cancer cohorts, ZRANB2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ZRANB2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZRANB2-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZRANB2-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

KIRC, SKCM, and LGG are the cancer types where ZRANB2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.911	0.835	<.001	93	view →
SKCM	DFS	Median	All	0.790	0.668	<.001	54	view →
LGG	DFS	Median	All	0.666	0.803	<.001	32	view →
LUSC	OS	Median	IV	0.255	0.851	.021	30	view →
UVM	OS	Median	III,IV	0.357	0.898	.001	22	view →
BRCA	OS	Quartile	III,IV	0.676	0.293	.001	22	view →
KIRP	OS	Tertile	III,IV	0.147	0.669	.003	18	view →
BLCA	DFS	Quartile	III,IV	0.504	0.347	.010	17	view →
LUAD	OS	Median	All	0.841	0.733	.011	15	view →
CESC	DFS	Tertile	II,III,IV	0.285	0.810	.005	14	view →
MESO	OS	Quartile	All	0.688	0.431	.017	11	view →
THCA	OS	Quartile	II,III,IV	0.950	0.993	.015	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ZRANB2-AS1–KIRC (OS)

Open the KIRC breakdown →