ZPR1

Across TCGA pan-cancer cohorts, ZPR1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZPR1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ZPR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZPR1 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and COAD are the cancer types where ZPR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.606	0.843	.003	26	view →
PDAC	DFS	Quartile	III,IV	0.220	0.979	.010	8	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZPR1–CCRCC (DFS)

Open the CCRCC breakdown →