ZPLD1

Across TCGA patient cohorts, ZPLD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,081 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZPLD1-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Vesicle cargo loading, and Positive regulation of protein autophosphorylation. Each is linked with ZPLD1 in more than 21 cancer types. Because this analysis shows association rather than direction, both ZPLD1-to-partner and partner-to-ZPLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by ZPLD1-low versus ZPLD1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZPLD1→partner) and Y-score (partner→ZPLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	COPII-coated vesicle cargo loading →	+0.083	+0.328	<.001	.001	3	22
STAD	Vesicle cargo loading →	+0.091	+0.318	<.001	<.001	3	20
TGCT	Positive regulation of protein autophosphorylation →	+0.063	+0.167	<.001	<.001	3	19
STAD	Osteoclast differentiation →	+0.050	+0.214	<.001	<.001	3	19
STAD	Substrate-dependent cell migration →	+0.081	+0.331	<.001	<.001	3	18
ESCA	Cell-matrix adhesion →	+0.066	+0.312	<.001	<.001	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,081 associations by consensus.

COPII-coated vesicle cargo loading by ZPLD1 expression — ESCA

Explore this box plot interactively →