ZPLD1

Across TCGA patient cohorts, ZPLD1 mutation is significantly associated with the RNA expression of many other genes, with 3,971 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZPLD1-associated genes across cancer lineages are NBPF5P, RNU6-1207P, and GMPS. Each is linked with ZPLD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZPLD1-to-partner and partner-to-ZPLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NBPF5P grouped by ZPLD1-low versus ZPLD1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZPLD1→partner) and Y-score (partner→ZPLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NBPF5P →	+0.023	+1.175	.002	.009	3	3
COAD	RNU6-1207P →	+0.519	+3.452	<.001	.009	3	3
LUAD	GMPS →	+0.590	+3.471	.002	.002	3	3
SKCM	MRPL3 →	+0.333	+1.330	.002	.004	3	3
UCEC	MED6 →	+0.470	+4.087	.001	<.001	3	3
UCEC	SNRPG →	+0.538	+2.212	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,971 associations by consensus.

NBPF5P by ZPLD1 expression — SKCM

Explore this box plot interactively →