Across TCGA patient cohorts, ZP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,414 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZP3-associated proteins across cancer lineages are PUS7, FOXK1, and NSUN5. Each is linked with ZP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZP3-to-partner and partner-to-ZP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZP3→partner) and Y-score (partner→ZP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PUS7 →	+0.452	+0.635	<.001	<.001	3	7
LUAD	FOXK1 →	+0.296	+0.867	<.001	<.001	3	6
HNSC	NSUN5 →	+0.347	+1.038	<.001	<.001	3	6
HNSC	MEPCE →	+0.377	+0.850	<.001	<.001	3	6
BRCA	MPHOSPH10 →	+0.381	+0.838	<.001	<.001	3	6
OV	YWHAG →	+0.290	+0.936	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,414 associations by consensus.

Exploration

ZP3 survival (RNA) · tumor vs normal (RNA) · all ZP3 data types