Across TCGA cell cohorts, ZP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,404 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZP3-associated GO terms across cancer lineages are Regulation of binding of sperm to zona pellucida, Negative regulation of binding of sperm to zona pellucida, and Regulation of acrosome reaction. Each is linked with ZP3 in more than 19 cancer types. Because this analysis shows association rather than direction, both ZP3-to-partner and partner-to-ZP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZP3→partner) and Y-score (partner→ZP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of binding of sperm to zona pellucida →	+2.098	+3.008	<.001	<.001	3	20
SOFT_TISSUE	Negative regulation of binding of sperm to zona pellucida →	+1.802	+2.461	<.001	<.001	3	20
PANCREAS	Regulation of acrosome reaction →	+1.508	+1.552	<.001	<.001	3	15
KIDNEY	Positive regulation of acrosome reaction →	+1.728	+2.295	<.001	<.001	3	15
PANCREAS	Binding of sperm to zona pellucida →	-0.156	-1.333	<.001	.003	3	14
LIVER	Regulation of acrosomal vesicle exocytosis →	+0.998	+2.128	.007	.002	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,404 associations by consensus.

Exploration

ZP3 survival (RNA) · tumor vs normal (RNA) · all ZP3 data types