Across TCGA cell cohorts, ZNRF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,808 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNRF3-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Positive regulation of DNA metabolic process, and Regulation of DNA repair. Each is linked with ZNRF3 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNRF3-to-partner and partner-to-ZNRF3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNRF3→partner) and Y-score (partner→ZNRF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of T-helper 17 cell lineage commitment →	+0.218	+1.072	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA metabolic process →	+0.052	+0.700	<.001	<.001	3	13
LIVER	Regulation of DNA repair →	+0.061	+1.278	.003	.001	3	13
URINARY_TRACT	P-body assembly →	+0.100	+0.668	.005	.008	3	12
BREAST	Nucleosome organization →	+0.080	+0.746	.009	.003	3	12
BONE	DNA replication-dependent chromatin assembly →	+0.158	+0.610	.001	.007	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,808 associations by consensus.

Exploration

ZNRF3 survival (RNA) · tumor vs normal (RNA) · all ZNRF3 data types