Across TCGA patient cohorts, ZNRF2P2 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNRF2P2-associated genes across cancer lineages are YWHAQP7, RNU105C, and ALX3. Each is linked with ZNRF2P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNRF2P2-to-partner and partner-to-ZNRF2P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNRF2P2→partner) and Y-score (partner→ZNRF2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YWHAQP7 →	+0.149	+3.155	.001	.004	3	1
COAD	RNU105C →	+0.427	+7.741	<.001	.009	3	1
UCEC	ALX3 →	+0.795	+4.007	<.001	.001	3	1
UCEC	SSTR5 →	+1.100	+3.871	<.001	.002	3	1
UCEC	RN7SL147P →	+0.307	+4.398	<.001	<.001	3	1
UCEC	RN7SL140P →	+0.122	+3.997	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

ZNRF2P2 survival (RNA) · tumor vs normal (RNA) · all ZNRF2P2 data types