Across TCGA patient cohorts, ZNRF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,166 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNRF1-associated proteins across cancer lineages are EDC4, MVD, and RRBP1. Each is linked with ZNRF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNRF1-to-partner and partner-to-ZNRF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNRF1→partner) and Y-score (partner→ZNRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EDC4 →	+0.264	+0.458	<.001	.002	3	6
OV	MVD →	+0.467	+0.629	.001	.002	2	5
LSCC	RRBP1 →	-0.367	-0.492	<.001	<.001	3	4
BRCA	IMPACT →	-0.291	-0.362	<.001	<.001	3	4
PDAC	KDM1A_S166 →	+0.378	+0.362	<.001	<.001	3	4
BRCA	TERF2_S365 →	+0.652	+0.513	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,166 associations by consensus.

Exploration

ZNRF1 survival (RNA) · tumor vs normal (RNA) · all ZNRF1 data types