Across TCGA cell cohorts, ZNRF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,344 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNRF1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of RNA splicing, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ZNRF1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNRF1-to-partner and partner-to-ZNRF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNRF1→partner) and Y-score (partner→ZNRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of myoblast fusion →	+0.103	+1.042	<.001	<.001	3	12
BONE	Negative regulation of RNA splicing →	+0.087	+0.964	.004	.001	3	12
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+0.953	<.001	<.001	3	12
OESOPHAGUS	Regulation of cell fate specification →	+0.130	+1.035	.001	.008	2	13
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.094	+1.053	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.088	+1.303	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,344 associations by consensus.

Exploration

ZNRF1 survival (RNA) · tumor vs normal (RNA) · all ZNRF1 data types